Description

Nausea is the most common side effect of semaglutide followed by diarrhea or constipation. The very low starting dose is intentional, so that your body can adjust to the medication. Most symptoms improve with time. While individual results will vary, the average weight loss in the clinical trials was approximately 15% of body weight. Semaglutide is based on what is called a GLP-1 agonist. GLP-1 stands for Glucagon Like Peptide, which is a hormone that is secreted naturally in the body by the gut. It helps regulate your metabolism which has a lot to do with insulin, etc. The thing about these peptides and what makes them different, is that they regulate the output of these hormones in your body:

* Insulin
* Glucagon

Both of these hormones are secreted by the pancreas.

This drug works in a number of different ways. Here’s a breakdown:

* It helps insulin secretion by the pancreas. Remember that insulin takes the sugar in your blood and puts it into the cells. That’s where you want it for energy.

* It also decreases the output of glucagon. The pancreas secretes glucagon where you’re fasting, when you’re hungry, and when your blood sugars are low. Glucagon stimulates the liver to put out glucose. Therefore, it decreases glucagon and indirectly decreases the liver output of glucose so you you won’t have as much blood sugar. Note: that’s why these medications work for diabetes.

* There’s also evidence that it decreases the appetite center in the brain as well.

So there’s actually four ways this drug works, and we’ve had tremendous success with it.
Contraindications: You can’t take it if you’ve had Pancreatitis (rare), Medullary Cancer of the Thyroid (extremely rare), MEN Syndrome 2 (extremely rare).

Semaglutide Dosing Weeks:

1-4 0.25 mg (10 units)
5-8 0.5 mg (20 units)
9-12 1mg (40 units)
13-16 1.7 mg (68 units)
17 and on 2.4 mg (96 units)

Note: if you are losing on your current dose you do not have to increase to the next dos